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Experience the completely redesigned Brooks Glycerin 22, made with all-new DNA Tuned foam to create plush cushioning with responsive toe-offs
- Offset
- 10 mm
- Weight
- 10.2 oz
- Support
- Neutral - Neutral shoes allow the foot to move and flex with minimal guidance.
- Cushion
- high
Treat Your Feet to Cushy Comfort
The Brooks Glycerin 22 is a plush, high-cushion trainer that’s seen a complete midsole upgrade this time around. This iteration features new DNA Tuned cushioning, a finely-tuned, nitrogen-infused foam that creates different zones of comfort. Larger cells in the heel give you a softer feeling while the tightly packed cells create a more responsive experience at toe-off.
Brooks didn’t stop at a midsole redesign, they kept the upgrades coming with an all-new double-jacquard mesh upper. This upper feels more luxurious than the previous warp-knit material, adding thick cushion around your heel and ankle. To help increase the longevity of the Glycerin 22, strategically placed rubber is used along the outsole, enhancing the overall traction and durability.
Features & Benefits:
- DNA Tuned foam cushioning is nitrogen-infused for a plush yet responsive experience
- New engineered double jacquard knit upper adds flexibility for a more accommodating fit
- Rubber outsole provides enhanced grip and traction on various surfaces
- A broad platform helps stabilize your foot to encourage smoother transitions
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Reviews
Based on 8 Verified Reviews
100%
Would Recommend This Product
Emin Qarayev
September 01, 2026
Amazing running shoes!
Super comfortable with great cushioning. Perfect for both workouts and daily walks. Highly recommend!
Anonymous
August 11, 2026
Brooks Glycerin 22
Excellant fit !
David Archacki
April 09, 2026
Happy Customer
Item was shipped quickly, arrived and was more than explained in description. Very happy 😃
Anonymous
March 18, 2026
Brooks Glycerine 22
Like the colors on the shoe, fairly comfortable although haven't had a chance yet to really tax the shoe.
Claire Willis
June 01, 2025
Great shoes
First and supported since I have very very flat feet that pronate
Tyler
April 03, 2025
Another great addition to the Brooks family [Staff Review]
I traditionally prefer soft, plush, high-cushion shoes and the Glycerin continues to be an excellent option in that category. The new midsole has an excellent initial foot-feel and continues to hold its comfort mid-run and post-run. As someone with a wider foot, I found the upper to be accommodating and pleasant.
Adam Phillips-Silver
February 09, 2026
Solid daily miles
Initial impression is a highly cushioned trainer with a high heel toe offset that is meant for cruising. The upper is plush to the point of needing to lace looser and wear thinner socks to offset lack of breathability. Midsole has plenty of cush rear and in the forefoot with just a touch of rebound. This is not a bouncy shoe, but it also doesn't feel like a slab of foam that seems popular right now with max trainers. Outsole feels grippy enough for wet or lightly snowy pavement. Overall the feel seems sturdy and comfortable for lots of easy and recovery miles.
Mike Hoey
November 13, 2025
Firmer than version 21
Only have about 20 miles in these so far but seem a lot firmer than the Glycerin 21. Hope they soften up with more miles. For is great.
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